The oral anticoagulant dabigatran etexilate can be prostate-play a challenge when patients need acute surgery.Sepsis and acute renal failure exacerbate the anticoagulant effect.There is no specific reversal agent for dabigatran etexilate, but it can be removed by hemodialysis.We present a case where a patient treated with dabigatran etexilate was admitted to intensive care unit with severe sepsis ORG GREENS UNFLAVOURED and acute renal failure and in need of bilateral lower limp amputation due to ischemia.
The patient had severe coagulopathy and was treated with continuous venovenous hemofiltration in attempt to remove dabigatran etexilate before surgery.